1472 Research Article The anti-invasive effect of lucidenic acids isolated from a new Ganoderma lucidum strain Chia-Jui Weng1 , Chi-Fai Chau1 , Kuang-Dee Chen2 , Deng-Hai Chen2 and Gow-Chin Yen1 1 Department of Food Science and Biotechnology, National Chung...
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1472 Research Article The anti-invasive effect of lucidenic acids isolated from a new Ganoderma lucidum strain Chia-Jui Weng1 , Chi-Fai Chau1 , Kuang-Dee Chen2 , Deng-Hai Chen2 and Gow-Chin Yen1 1 Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan 2 Biotechnology Research and Development Institute, Double Crane Group, Ching-Shui Village, Yen-Shui Township, Tainan Hsien, Taiwan Ganoderma lucidum is a well-known mushroom with various pharmacological effects that has been used for health and longevity purposes. The objective of this study was to investigate the anti-invasive effect of lucidenic acids isolated from a new G. lucidum strain (YK-02) against human hepatoma car- cinoma (HepG2) cells. Triterpenoid components in the ethanol extract of G. lucidum (YK-02) were separated by means of a semi-preparative RP HPLC. Four major peaks were separated and crystal- lized from triterpenoids fraction, and were identified as lucidenic acids A, B, C, an
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