Genomic History Africa

R ES E A RC H CHOLERA isolates and provided a preliminary view of over- all disease transmission on the continent. Other genomic studies dealing with epidemics in Africa Genomic history of the seventh have been published, but these studies focused on the... More

R ES E A RC H CHOLERA isolates and provided a preliminary view of over- all disease transmission on the continent. Other genomic studies dealing with epidemics in Africa Genomic history of the seventh have been published, but these studies focused on the disease exclusively at national or regional pandemic of cholera in Africa levels (14–17). We reconstructed the spatiotemporal spread of cholera across the continent during the 7P by François-Xavier Weill,1,2* Daryl Domman,2 Elisabeth Njamkepo,1 Cheryl Tarr,3 analyzing the genomes of 1070 V. cholerae El Tor Jean Rauzier,1 Nizar Fawal,1 Karen H. Keddy,4,5 Henrik Salje,6,7 Sandra Moore,8 isolates, including 714 new isolates sequenced Asish K. Mukhopadhyay,9 Raymond Bercion,10,11 Francisco J. Luquero,12 in this study (table S1 and fig. S1). The newly Antoinette Ngandjio,13 Mireille Dosso,14 Elena Monakhova,15 Benoit Garin,11† sequenced African isolates (n = 569) were se- Christiane Bouchier,16 Carlo Pazzani,17 Ankur Mutreja,18,19 Roland Gr Less