Report on Ethiology, epidemiology, pathogenesis, clinical features and the treatment principles of cholera. Dehydration – Rehydration. Report prepared by 1. Dr. Sajid Mahmood, MD (EU), Accident & Emergency Department, NHS Royal infirmary Liverpool United

-pg-1 Ethiology, epidemiology, pathogenesis, clinical features and the treatment principles of cholera. Dehydration – Rehydration. Cholera is a acute diarrheal disease involving the entire small bowel and that can cause death due to dehydration within... More

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Ethiology, epidemiology, pathogenesis, clinical features and the treatment principles of cholera.

Dehydration – Rehydration.

Cholera is a acute diarrheal disease involving the entire small bowel and that can cause death due to dehydration
within several hours.

1) Etiology:
- Vibrio Cholerae: It is curved, motile, flagellated Gr Negative bacteria ( Aerobic Rod)
- The organism is killed by 100°C temperature in few seconds but can survive in ice for up to 6 weeks.

- 2 Main sero groups – O1 & O139 Bengal
O1 has 2 biotypes – classical & El tor and 3 serotypes Inaba, Ogawa, Hikojima (All three strains are
pathogenic)
- Vibra Cholerae Vibrae Heamolyticus
Non Invasive Invasive
Affects Small Bowel Affects Colon
(Proximal Mainly)
- El Tor is the major cause of cholera now as it is a hardier organism.
Infection with El Tor is frequently
unrecognized because it produces milder clinical symptoms.

2) Epidemiology:
- Hosts : Human
- Cholera is spread by ingestion of H2O, seafood or other Less